HCV感染 - 医学翻译 -中翻英

winifred 2018年8月3日 17:13

原文 HCV包括6种常见基因型,其中HCV基因1b型是中国最常见的基因亚型,占所有HCV感染者的56.8% [2]。肝硬化是HCV感染的最常见疾病进展,大约20%的患者可出现。肝硬化的并发症包括肝功能代偿不全(腹水、肝性脑病、静脉曲张破裂出血、肝肾综合征或肝合成功能障碍)和肝细胞癌,后者每年的发生率为3%左右。如果不进行肝脏移植,失代偿性肝硬化可导致患者5年内的病死率达到 50% ~ 72%。长期随访研究显示,基因1b型患者发生肝细胞癌(HCC)的风险高于其他基因亚型[3]。

译文 HCV includes 6 common genotypes, among which HCV gene 1b is the most common subtype in China, accounting for 56.8% of all HCV infections. Cirrhosis is the most common progression of HCV infection, with which nearly 20 per cent patients are afflicted. Complications of cirrhosis include hepatic dysfunction (ascites, hepatic encephalopathy, varicose veins caused bleeding, hepatorenal syndrome, or hepatic dysfunction) and hepatocellular carcinoma, which occurs among 3% of patients every year. Without a liver transplant, decompensated cirrhosis can result in a mortality rate of 50% to 72% within 5 years. Long-term follow-up studies have shown that patients with subtype 1b have a higher risk of hepatocellular carcinoma (HCC) than other subtypes. 。