药代动力学翻译-中译英

Raymond Dec. 4, 2018, 4:14 p.m.

Translation exercises


盐酸萘替芬:健康人单剂外用1%的盐酸萘替芬乳膏,约有6%的剂量被吸收,盐酸萘替芬及其代谢产物通过尿液和粪便排泄,半衰期约为2~3 天。盐酸萘替芬透过表皮层后有足够的浓度抑制皮肤真菌的生长。

[Pharmacokinetics] Naatifen hydrochloride: External single dose of 1% naatifen hydrochloride cream for healthy people, about 6% of it is absorbed. Naatifen hydrochloride and its metabolites excreted through urine and feces, with a half-life of about 2 to 3 days. The concentration of naftiofen hydrochloride is sufficient to inhibit the growth of skin fungi after passing through the epidermis.

酮康唑:在Beagle 犬的正常皮肤和擦伤的皮肤上涂擦2%的酮康唑乳膏,剂量80mg/天,连用28 天,血中未检出药物(最低检出限度为2ng/ml)。健康志愿者单剂外用2%酮康唑乳膏于胸、背和手臂处,72 小时内血中未检出药物(最低检出限度为5ng/ml)。

Ketoconazole: Apply 2% ketoconazole cream on the normal skin and abrasioned skin of Beagle dogs at a dose of 80mg/day for 28 days consecutively, no detectable drug in the blood (limit of detection was 2ng/ml). A single dose of 2% ketoconazole cream was applied on the chest, back and arms of healthy volunteers, and no drug was detected in the blood within 72 hours (limit of detection was 5 ng/ml).

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